2002 Invasive Lobular Carcinoma of the Breast: Mammographic Characteristics and Computer-Aided Detection Authors: Evans WPE, Warren Burhenne LJ, Laurie L, O'Shaughnessy KF, and Castellino RA. Published: Radiology 2002; 225: 182-189. PURPOSE: To evaluate the ability of a computer-aided detection system to mark these invasive lobular carcinomas. CONCLUSION: On the screening mammograms showing biopsy-proved cancers, the sensitivity of the computer-aided detection system was 91% (86/ 94). Thirty-one of the 40 prior mammograms showed retrospectively visible findings, and 77% (24/3)30151 were marked by the computer-aided detection system. Spiculated masses and architectural distortions are the predominant appearances of invasive lobular carcinoma, and a computer-aided detection system correctly marked a high percentage of invasive lobular carcinoma lesions.   Computer-Aided Detection In Direct Digital Full-Field Mammography: Initial Results Authors: Baum F, Fischer U, Obenauer S, and Grabbe E Published: Eur. Radiol 2002; 12: 3015-3017. PURPOSE: To evaluate a CAD system (V2.3, R2 Technology ) for 63 cases of histologically proven breast cancer (14 microcalcifications, 37 masses, and 12 both) diagnosed with FFDM (Senographe 2000D, GE Medical Systems). CONCLUSIONS: CAD sensitivity was 89% for microcalcifications [CI95%=(70%; 98%)] and 81% for masses [CI95%=(67%; 91%)]. The overall rate of false-positive marks was 0.61 per image (0.35 microcalcification marks/image and 0.26 mass marks/image). Results are equivalent to those reported for CAD analysis of secondarily digitized image data.